Question VI. In the typical complement fixation test (CFT), [complete the senten

Question

Question VI. In the typical complement fixation test (CFT), [complete the sentence and assess each subsequent statement (44-55) as either factually correct (= “true”) or incorrect (= “false”)]:

44. a patient positive for the given disease will show an increase in complement in his blood and thus give a positive test.

45. a patient positive for the given disease will show a decrease in complement in his blood and thus give a positive test.

46. antibody-sensitized sheep red blood cells (sRBC) lyse if the patient has antigen being tested for.

47. sRBC lyse if the patient has antibody being tested for.

48. sRBC settle to the bottom if the patient has antibody being tested for.

49. sRBC settle to the bottom if the patient has antigen being tested for.

50. tested patients have equal amounts of complement in their serum.

51. tested patients differ in the amount of complement naturally found in their serum.

52. the amount of complement in the patient's blood is measured as an indicator for the presence of infection.

53. a patient's serum is heated to destroy complement and a measured amount of complement and antigen is added.

54. a patient's serum is heated to destroy complement and a measured amount of complement and antibody is added.

55. a patient's serum is heated to destroy antibodies and a measured amount of complement and antibody is added.

Explanation / Answer

44. a patient positive for the given disease will show an increase in complement in his blood and thus give a positive test. ------------> FALSE (The amount of complements present in patients serum is different from one another).

45. a patient positive for the given disease will show a decrease in complement in his blood and thus give a positive test. ------------> FLASE (The amount of complements present in patients serum is different from one another).

46. antibody-sensitized sheep red blood cells (sRBC) lyse if the patient has antigen being tested for. -----> FALSE

47. sRBC lyse if the patient has antibody being tested for. -----------> FALSE

48. sRBC settle to the bottom if the patient has antibody being tested for. ------> TRUE

49. sRBC settle to the bottom if the patient has antigen being tested for. -------> FALSE

50. tested patients have equal amounts of complement in their serum. ---------> FALSE

51. tested patients differ in the amount of complement naturally found in their serum. ---------> TRUE

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