***Biochemistry Consider the fatty acid below for questions 7-12 H2 CH H3C CSCOA
ID: 699219 • Letter: #
Question
***Biochemistry Consider the fatty acid below for questions 7-12 H2 CH H3C CSCOA H2 7. Which carbon(s) will be release first after one round of fatty acid oxidation? What is the product? 8. How many rounds of oxidation will this fatty acid undergo? 9. How many acetyl CoA molecules will be produced from this fatty acid? 10. How many FADH2-molecules (total) will be produced in the -oxidation process? 11, How many NADH molecules (total) will be produced will be produced in the - oxidation process? 12. How many ATP molecules will be produced after the fatty acid is completely oxidized to CO2? (how many CO2 molecules will be produced?) For accounting purposes assume that the starting point is the free fatty acid that has just entered the cellExplanation / Answer
For the given fatty acid with carbon = 12
7. First the two carbons CH2-COSCoA would be released after first cycle of beta oxidation. So breaks from carbonyl end, two carbon at a time.
Products formed are CH3-(CH2)8-CO-SCoA + CH3CO-SCoA
8. Rounds of beta oxidation needed = (12/2 - 1) = 5 rounds
9. number of acetylCoA produced = 6
10. Total FADH2 produced = 5
11. Total NADH produced = 5
12. with each NADH produces 2.5 ATP and FADH2 produces 1.5 ATP
Total number of ATP produced = 6 acetyl CoA x 12 ATP + 5 x 2.5 (FADH2 to ATP) + 5 x 1.5 (NADH to ATP) - 2 (for activation) = 90 ATP
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