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TRUE/FALSE: 01. ____ Koch’s postulates can be fulfilled by all known bacterial p

ID: 69661 • Letter: T

Question

TRUE/FALSE:

01. ____ Koch’s postulates can be fulfilled by all known bacterial pathogens with no limitations.

02. _____ The expression of virulence factors, like adhesion molecules, can influence the species specificity and tissue tropism of the bacterial pathogen.

03. __ Non-specific adherence of bacterial pathogens mediates strong attachment to host cells and tissues through adhesins.

04. __ Invasins are proteins that have local effects on host tissues and cells and promote spread of the bacterial pathogen.

05. __ Pathogenic bacteria have developed a sophisticated method to directly inject bacterial proteins into target host cells called the Type III secretion system (T3SS).

06.   __ It is not necessary for the eukaryotic host cell to express (transcriptionally or translationally) the receptor for bacterial adhesins.

07. __ The specific binding between antibody and antigen forms the basis of many important assays and techniques.

08. __ Monoclonal antibodies are antibodies produced by a single clone of B cells, so that they are all identical and recognize the same epitope of an antigen.

Explanation / Answer

01. __FALSE__ Koch’s postulates can be fulfilled by all known bacterial pathogens with no limitations.

Koch's postulates were applied to all diseases in a generalized manner, these postulates cannot be fulfilled by all known bacterial pathogens.

02. ___TRUE__ The expression of virulence factors, like adhesion molecules, can influence the species specificity and tissue tropism of the bacterial pathogen.

03. _TRUE_ Non-specific adherence of bacterial pathogens mediates strong attachment to host cells and tissues through adhesins.

04. _TRUE_ Invasins are proteins that have local effects on host tissues and cells and promote spread of the bacterial pathogen.