Two different mutants, A and B, were isolated from a Gram negative microorganism

Question

Two different mutants, A and B, were isolated from a Gram negative microorganism. The ID50 of mutant A is 100 times higher than the ID50 of the parental (non mutated, wild type) microorganism. However the ID50 of the parental and the mutant B microorganisms is the same. Select the correct statement

Mutations in microorganism A could be affecting genes encoding virulence determinants

Mutations in microorganism B could be affecting genes encoding virulence determinants

Mutations in microorganism B could be affecting genes encoding proteins required for the growth of the microorganism

All the statements above are correct

Microorganism in the normal flora can spread of antibiotic resistant genes

True

False

T and B cells are an essential part of the innate immune system

True

False

Mutations in microorganism A could be affecting genes encoding virulence determinants

Mutations in microorganism B could be affecting genes encoding virulence determinants

Mutations in microorganism B could be affecting genes encoding proteins required for the growth of the microorganism

All the statements above are correct

Microorganism in the normal flora can spread of antibiotic resistant genes

True

False

T and B cells are an essential part of the innate immune system

True

False

Explanation / Answer

1 Q). Mutations in microorganism A could be affecting genes encoding virulence determinants ----------> TRUE

2 Q). Microorganism in the normal flora can spread of antibiotic resistant genes -----> TRUE

3 Q). T and B cells are an essential part of the innate immune system -----> FALSE

Innate immunity is a nonspecific resistance that we have from the time of birth. Innate immunity is not triggered by the specific antigens; so, it is a non-specific defence system regardless of the type of invading agent. Our body is able to prevent the occurrence of any disease, entry of pathological organisms, and spread of infections through the innate immunity only.

Various defensive mechanisms of innate immunity include physical barriers, phagocytes, immune surveillance, interferons, complement system, inflammation and fever.

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