Duchenne Muscular Dystrophy is caused by a relatively rare X-linked recessive al

Question

Duchenne Muscular Dystrophy is caused by a relatively rare X-linked recessive allele (mutation). Use XM for a normal gene and Xm for the mutated allele. It causes progressive muscle degeneration and usually leads to death by age 20. An unaffected man marries a normal woman whose brother was affected by this disorder. Neither set of parents of the couple have muscular dystrophy. What is the probability their first child will be a son who is affected with the disease, how about a daughter? Explain, using a Punnett square(s), how you arrived at your answer.

Explanation / Answer

First child to be girl is 50%

50% Boy is affected

50% girl is carrier

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