Use this information to answer the next five questions: Five genes (A-E) that co

Question

Use this information to answer the next five questions: Five genes (A-E) that contribute to the weight of mice have been identified. The dominant alleles of each of these genes contribute equally, and in an additive way. Inbred strains of mice have been obtained, and those that are homozygous for all five recessive alleles are found to weigh 32g and those that are homozygous for all five dominant alleles are found to weigh 47g. The Fi are crossed to each other and the F2 are analyzed. The F1 is the expected weight of mice that have the genotype AABBccDdEe? Using the information in the question above, what is the expected frequency of F2 individuals of genotype AABBccDdEe? In the question above, how many different genotypes are possible in the F2? In the question above, how many different phenotypes (weight categories are possible in the F2? In the question above, how many F2 mice would you expect to need in order to see one with the same weight (ie., 32g) as the homozygous recessive parent?

Explanation / Answer

ion 1

dominant = AA BB CC DD EE = 47gms

recessive = aa bb cc dd ee = 32 gms

Other genotypes will have weight inbetween these values

therefore

Aa BB cc Dd Ee = 38 gms

ion 2

Multiply each genotpe frequency, AA BB cc Dd Ee = 25 % 25% 25% 50% 50%= 1/4x1/4x1/4x1/2x1/2 = 1/256

ion 3

In F2 generation   AA BB cc Dd Ee X AA BB cc Dd Ee

possible geneotypes are 243

ion 4

homozygous = 1 phenotype, heterozygous = 2 phenotype

therefore, 7 phenotypes

ion 5

aa bb cc dd ee = 32 gms ( 25 phenotypes)

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