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Lung disease is often divided into two broad categories: obstructive disease and

ID: 64500 • Letter: L

Question

Lung disease is often divided into two broad categories: obstructive disease and restrictive disease. Examples of obstructive disease are emphysema, chronic bronchitis, and asthma. Examples of restrictive disease are abnormalities of the spine and chest and diseases within the lungs that make them less elastic (“stiffer”), such as pulmonary fibrosis. Calculate the FEV1/FVC in the table below for obstructive and restrictive disease and compare to your values. How might these values be helpful diagnostically?

Volume (L)

Normal (your data)

Obstructive disease

Restrictive disease

FVC (L)

4

4

FEV1 (L)

1.8

3.5

FEV1/FVC (%)

FEV1/FVC : the normal value is 75-80%. Anything below this is

considered abnormal.

FVC: more than 80% of predicted value

FEV1: more than 80% of predicted value

FEV1% : 70 to 80%

Volume (L)

Normal (your data)

Obstructive disease

Restrictive disease

FVC (L)

4

4

FEV1 (L)

1.8

3.5

FEV1/FVC (%)

Explanation / Answer

Volume (L)

Normal (your data)

Obstructive disease

Restrictive disease

FVC (L)

5

4

4

FEV1 (L)

4

1.8

3.5

FEV1/FVC (%)

80%

45%

87.5%

Volume (L)

Normal (your data)

Obstructive disease

Restrictive disease

FVC (L)

5

4

4

FEV1 (L)

4

1.8

3.5

FEV1/FVC (%)

80%

45%

87.5%