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1) Which of the following statements about glycogen structure and utilization is

ID: 63417 • Letter: 1

Question

1) Which of the following statements about glycogen structure and utilization is FALSE?

Liver glycogen is used to buffer the overall blood glucose level during fasting

Glycogen is a polymer of glucose linked by -1,4 and -1,6 glycosidic linkages

Branched structure of glycogen allows for very rapid mobilization of free glucose monomers when necessary.

Glycogen structure allows compact packing of thousands of glucose molecules together

Eating a large meal promotes the breakdown of glycogen to allow for maximal energy for cells.

2)Which of the following statements about glucokinase and hexokinase (that catalyze the same reaction) is TRUE?

Hexokinase is only active in the liver where it can utilize multiple hexoses

While glucokinase requires ATP for its action, hexokinase requires GTP

Glucokinase has a higher capacity than hexokinase to convert glucose to glucose 6 phosphate

Glucokinase can act on multiple glucose-like sugars (such as galactose)

Hexokinase has a higher Km and easily handles all the glucose from a carbohydrate rich meal

3.) Which of the following statements is NOT true about aerobic glycolysis?

A. the rate limiting enzyme is phosphofructokinase 1 which converts fructose-6-phosphate to fructose-1,6-biphosphate

B. the pathway begins with the action of the enzyme glucokinase or hexokinase

C. the pathway is allosterically inhibited by AMP and ADP

D. the pathway produces NADH and pyruvate

A.

Liver glycogen is used to buffer the overall blood glucose level during fasting

B.

Glycogen is a polymer of glucose linked by -1,4 and -1,6 glycosidic linkages

C.

Branched structure of glycogen allows for very rapid mobilization of free glucose monomers when necessary.

D.

Glycogen structure allows compact packing of thousands of glucose molecules together

E.

Eating a large meal promotes the breakdown of glycogen to allow for maximal energy for cells.

Explanation / Answer

1)c

2)E

3)C