TRUE/FALSE: 09. _____ T cells encounter their specific antigen while circulating
ID: 63359 • Letter: T
Question
TRUE/FALSE:
09. _____ T cells encounter their specific antigen while circulating in the blood.
10. _____ TLRs are molecules that recognize PAMPs and are expressed on dendritic cells.
11. _____ The IL-2 receptor on an activated T cell increases in affinity because of the addition of a third chain.
12. _____ CD28 binds to B7 family members with higher affinity than CTLA-4, which is why CD28 gives a positive signal to T cells whereas CTLA4 gives a negative signal.
13. _____ CD4 T cells recognize antigen presented by MHC class II.
14. _____ CD8 T cells are the only T cells that can be cytolytic.
15. _____ Gene knock out mice are a good way to determine the function of
Explanation / Answer
9. False. T-cells cannot recognize antigens as such, they can recognize only processed antigens presented by a professional antigen presenting cell
10. True. Toll like receptors are present on dendritic cells, monocytes, macrophages, mast cells and B cells. They can recognize pathogen associated molecular patterns
11. True
12.. True
13. True. CD4 cells recognize antigens presented by APC with their MHC-II
14. True
15. True
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