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TRUE/FALSE: 09. _____ T cells encounter their specific antigen while circulating

ID: 63359 • Letter: T

Question

TRUE/FALSE:

09. _____ T cells encounter their specific antigen while circulating in the blood.

10. _____ TLRs are molecules that recognize PAMPs and are expressed on dendritic cells.

11. _____ The IL-2 receptor on an activated T cell increases in affinity because of the addition of a third chain.

12. _____ CD28 binds to B7 family members with higher affinity than CTLA-4, which is why CD28 gives a positive signal to T cells whereas CTLA4 gives a negative signal.

13. _____ CD4 T cells recognize antigen presented by MHC class II.

14. _____ CD8 T cells are the only T cells that can be cytolytic.

15. _____        Gene knock out mice are a good way to determine the function of

Explanation / Answer

9. False. T-cells cannot recognize antigens as such, they can recognize only processed antigens presented by a professional antigen presenting cell

10. True. Toll like receptors are present on dendritic cells, monocytes, macrophages, mast cells and B cells. They can recognize pathogen associated molecular patterns

11. True

12.. True

13. True. CD4 cells recognize antigens presented by APC with their MHC-II

14. True

15. True