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1. To maintain a proper rate of the TCA cycle, oxaloacetate is replenished perio

ID: 62175 • Letter: 1

Question

1. To maintain a proper rate of the TCA cycle, oxaloacetate is replenished periodically. To increase [oxaloacetate], ___X____ is turned on but the rest step of TCA cycled is turned off by phosphorylation of __Y__.

A) X = Glyoxylate cycle     ::::::     Y = isocitrate dehydrogenase

B) X = Glyoxylate cycle     ::::::     Y = isocitrate lyase

C) X = Q cycle                    ::::::     Y = isocitrate dehydrogenase

D) X = Q cycle                    ::::::     Y = isocitrate lyase

E) None of the above.

2. Assume you have three NADH and one FADH2. Calculate the total numbers of H+ pumped into the inter-membrane space and the maximal number of ATP produced inside the matrix.

A)    40 H+   and     12 ATP
B)    40 H+   and     11 ATP
C)    36 H+   and     12 ATP

D)    36 H+   and     11 ATP
E)    None of the above.

Explanation / Answer

1. To maintain a proper rate of the TCA cycle, oxaloacetate is replenished periodically. To increase [oxaloacetate], Glyoxylate cycle is turned on but the rest step of TCA cycled is turned off by phosphorylation of isocitrate dehydrogenase.

2. Assume you have three NADH and one FADH2. Calculate the total numbers of H+ pumped into the inter-membrane space and the maximal number of ATP produced inside the matrix.

D)    36 H+   and     11 ATP