1) Below are two homologous chromosomes – one with an inversion. A crossover occ
ID: 60240 • Letter: 1
Question
1) Below are two homologous chromosomes – one with an inversion. A crossover occurs between the D and E genes. Below, select what type of inversion is seen here, and all of the possible gametes produced here.
ABC?DEFGHIJKL
afed?cbghijkl
a) ABC?Defa non-recombinant
b) LKJIHGFEefghijkl recombinant
c) LKJIHGFEefghijkl non-recombinant
d) pericentric inversion
e) ABC?DEFGHIJKL non-recombinant
f) ABC?Dd?cbghijkl recombinant
g) ABC?Defa recombinant
h) LKJIHGFEd?cbghijkl recombinant
i) LKJIHGFEd?cbghijkl non-recombinant
j) ABC?Dd?cbghijkl non-recombinant
k) paracentric inversion
l) afed?cbghijkl recombinant
m) afed?cbghijkl non-recombinant
n) ABC?DEFGHIJKL recombinant
2) A female patient has had a lifelong battle with sever muscle weakness. When her doctor examines her genome, he saw the following. What type of chromosomal mutation does she have?
choose from one of the answer choices below:
a) inversion
b) Nonreciprocal translocation
c) Reciprocal translocation
d) duplication
e) Robertsonian translocation
f) Deletion
3) Below are two non-homologous chromosomes. For each choice, select the best match for the type of mutation that has occurred.
XYZ?ABCDE
FGHIJ?KLMN
1) XYZ?ADE =
2) XYZ?ABCBCDE =
3) FGHIJ?KLMHGN =
4) XYZ?AE
FGHBCDIJ?KLMN =
5) FGHLK?JIMN =
6) XYZ?ABCMN
FGHIJ?KLDE =
7) FGHIJ?KLMNABCDE (no 2nd chromosome) =
8) XYZ?ADCBE =
for each of the above choices, select the best match from the options below:
a) nonreciprocal translocation
b) deletion
c) pericentric inversion
d) reciprocal translocation
e) reverse duplication
f) Robertsonian translocation
g) paracentric inversion
h) tandem duplication
a) nonreciprocal translocation
b) deletion
c) pericentric inversion
d) reciprocal translocation
e) reverse duplication
f) Robertsonian translocation
g) paracentric inversion
h) tandem duplication
Explanation / Answer
2. the type of the chromosomal mutaion occurs in the female with muscle weakness is ;
Option a ; deletion. as there is a deletion of the one long arm of the chromosome .
3.
Option 1 ; matching is b , deletion
Option 2; matching is e , reverse duplication.
Option 3 ; matching is h, tandem duplication
Option 4; option a, non reciprocal translocation
Option 5; Option C ,pericentric inversion
Option 6; Option f ,robertsonian translocation
Option 7; option D ,reciprocal translocation
option 8 ;option G ,Paracentric inversion
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