1) What is a prokaryotic operon? How are the genes related? How is this differen
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Question
1) What is a prokaryotic operon? How are the genes related? How is this different from Eukaryotes?2) How do miRNA and siRNA silence gene translation? Do they silence gene transcription? 1) What is a prokaryotic operon? How are the genes related? How is this different from Eukaryotes?
2) How do miRNA and siRNA silence gene translation? Do they silence gene transcription? 1) What is a prokaryotic operon? How are the genes related? How is this different from Eukaryotes?
2) How do miRNA and siRNA silence gene translation? Do they silence gene transcription?
2) How do miRNA and siRNA silence gene translation? Do they silence gene transcription?
Explanation / Answer
1) What is a prokaryotic operon? How are the genes related? How is this different from Eukaryotes?
Operon is a functioning unit of genome, cluster of genes coregulated by single promotor. Genes are regulated in such a way that they are all turned on or off at the same time.
The genes are arranged flanking together as a stretch of DNA such that their expression can be easily coregulated. All genes together become a product of single mRNA. The gene products act together to make function a single metabolite.
Since eukaryotes have more genes and are spread across multiple chromosomes in complexity genome. More steps are involved in processing of mRNA by excising introns, and also variety complexity control mechanism in transcription and translation makes differ from prokaryotes.
2) How do miRNA and siRNA silence gene translation? Do they silence gene transcription?
miRNA express endogenously and exogenously derived siRNA induces degradation of messenger RNA to prevent translation.
Yes they do silence gene transcription, Chromatin dependent gene silencing involves the assembly of small RNA complexes on nascent transcripts and activates transcriptional gene silencing (TGS) and co-transcriptional gene silencing (CTGS) events.
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