For point 3 Describe: Which ligand gated ion channels are open? Which are closed
ID: 59501 • Letter: F
Question
For point 3 Describe:Which ligand gated ion channels are open? Which are closed.
Which voltage gated channels are open? Which are closed.
Is there a net sodium current, potsassium current, or neither. Which ligand gated ion channels are open? Which are closed.
Which voltage gated channels are open? Which are closed.
Is there a net sodium current, potsassium current, or neither. Action Potential 3 5 Action potential 0 Depolarization-Repolarization Threshold 2 -55 Generator potential 7 -70 6 Resting membrane potential Hyperpolarization Time
Explanation / Answer
Ligand-gated channels will open upon binding of chemical messenger to its receptor.
During depolarization, the excitatory neurotransmitter ex. Ach (ligand) will bind to their receptors (nAChRs) leads to opening of Na+,Ca+ channels and closing of K+ channels.
During hyperpolarization (>-70mV), the inhibitory neurotransmitter ex. GABA binds to its receptors that opens Cl-/K+ channels and closes Na+ or Ca+ channels.
At resting potential (-70 mV) both Na+ and K+ voltage-gated channels will be closed.
During depolarization (action potential), voltage-gatted Na+ channels will be opened and K+ channels will be closed.
During repolarization, voltage-gated K+ channels will be opened and Na+ channels will be closed.
During hyperpolarization (more negative), K+ channels and/or Cl- channels will be opened and Na+ or Ca+ channels will be closed.
In the action potential (+90mV; -55mV to +35mV), there will be a net Na+ current while depolarization (-70mV to +35mV) and there will be net K+ current while repolarization (+35mV to -70mV), but at the resting state (-70mV), there is no net current and the membrane have negative charge inside (3Na+ outside and 2K+ inside).
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