[] are integrin-containing anchoring junctions that attach cells to [] o

ID: 57147 • Letter: #

Question

[____] are integrin-containing anchoring junctions that attach cells to [____] of the underlying

extracellular matrix. Integrins are a large family of heterodimeric cell-surface, transmembrane

proteins that link to the [____] and mediate both cell-cell and cell-matrix adhesions and inside-out and

outside-in signaling in tissues. [____], constructed of multiple copies of connexins, form transmembrane

[____] between adjacent cells, permitting direct metabolic and electrical coupling.

(1) Desmosomes; collagen; intermediate filaments; Plasmodesmata; linkages

(2) Hemidesmosomes; laminin; actin cytoskeleton; Gap junctions; channels

(3) Focal adhesions; basal lamina; adhesion belt; Intercellular channels; junctions

(4) Tight junctions; actin filaments; cytoskeleton; Connexons; pores;

(5) Occluding junctions; the surface; intermediate filaments; Connexons; aqueous channels

Option 2 is right

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