The locations of six deletions have been mapped to the Drosophila chromosome as

Question

The locations of six deletions have been mapped to the Drosophila chromosome as shown in the diagram below. Recessive mutations (“a”, “b”, “c”, “d”, “e”, “f”, and “g”) found in seven genes are known to be located in the same region as the deletions, but the order of the mutations (or genes) on the chromosome is not known. The phenotypes observed in heterozygous offspring when flies homozygous for recessive mutations are crossed with flies homozygous for deletion mutations are summarized in the accompanying table. The symbol “m” represents a mutant phenotype and a plus sign (+) represents the wild type phenotype. On the basis of this data, determine the relative order of the seven mutant genes on the chromosome

Explanation / Answer

The correct order of the genes is (b-c-d-e-a-f-g)

Deletion 1: b,c,d

Deletion 2: c,d

Deletion 3: d,e

Deletion 4: d,e,a

Deletion 5: a,f,g

Deletion 6: d,e,a,f

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