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The dopamine beta-hydroxylase is an important enzyme found in neural tissue that

ID: 565189 • Letter: T

Question

The dopamine beta-hydroxylase is an important enzyme found in neural tissue that is responsible for creating norepinephrine.  While experimenting using in-vitro model of dopamine reactivity using PC 12 cells, you find out that a substance DB 15 can act as an inhibitor. You have so far studied three different concentrations of DB 15 (I1, I2, and I3) such that I1<I2<I3. Using the graph below identify and discuss the nature of the inhibitory mechanims DB15 has.

Please show all work and explain thoroughly. Thanks!

(v10-1,1/s10,13 (v5-1, 1/ssh) (va 1,1/s, 13) (v3-1,1/s3,lo) (v,-1,1/s7,12) (v21,1/s2, Io) (v 1,1/s4,)

Explanation / Answer

Solution:

DB15 is an inhibitor so it will inhibits the transmition of dopamine to norepinephrine.

That's y graphical representation shows fall in graph by acting using PC12 that is bcoz they work on the down order as 1<2<3

The nature of DB15 is inhibitory.

At the different concentrations it will shows the downfall of graphical representation. And leads to inhibition of dopamine.

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