The N-terminus of an integral membrane protein which projects into the lumen of

Question

The N-terminus of an integral membrane protein which projects into the lumen of the ER may also be found:

as a soluble cytoplasmic protein

with N-terminus protruding out of the cytoplasmic surface of the cell membrane into the cytosol

with N-terminus protruding out of the inner mitochondrial membrane

with N-terminus protruding out of the exoplasmic surface of the cell membrane into the extracellular space

with N-terminus protruding out of the nucleus from the nuclear membrane

as a soluble cytoplasmic protein

with N-terminus protruding out of the cytoplasmic surface of the cell membrane into the cytosol

with N-terminus protruding out of the inner mitochondrial membrane

with N-terminus protruding out of the exoplasmic surface of the cell membrane into the extracellular space

with N-terminus protruding out of the nucleus from the nuclear membrane

Explanation / Answer

Correct answer is: With N-terminus protruding out of the cytoplasmic surface of the cell membrane into the cytosol.

The signals of N-termal sequence is removed during translocation across the membrane and protuded out of the cytoplasmic surface of the cell membrane int to the cytosol.

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