How does the process of On center Off surround vs. Off center On surround work i
ID: 56397 • Letter: H
Question
How does the process of On center Off surround vs. Off center On surround work in the receptive fields of the retina?
I just want to make sure that I have this process correct if someone could please check my work that would be awesome.
On Center Off Surround
Direct Pathway
1. Light onto the center of the receptive field hyperpolarizes the photoreceptor cell.
2. The photoreceptor cell releases less glutamate
3. Less glutamate binds to mGluR6 inhibitory receptors on the bipolar cell.
4. Less activation of mGluR6 receptors leads to depolarization of the bipolar cell.
5. Depolarization of the bipolar cell results in more glutamate release by the bipolar cell.
6. More glutamate then binds to AMPA /NMDA receptors on the retinal ganglion cell leading to more action potentials
Indirect Pathway
1. Light onto the surround of the receptive field hyperpolarizes the photoreceptors
2. The photoreceptors release less glutamate
3. Less glutamate onto the AMPA receptors of the horizontal cell
4. Less activation or AMPA receptors on the horizaontal cell leads to hyperpolarization of the horizontal cell.
5. Hyperpolarization of the horizontal cell leads to less GABA release from the horizontal cellonto the center photoreceptor cell.
6. Less activation of GABA receptors on the center photorecetor cell leads to depolarization of the center photorecetor cell
7. Depolarization of the center photoreceptor cell leads to more glutamate release from the center photoreceptor cell
8. More glutamate release from the center photoreceptor cell leads to mor binding of glutamate onto mGluR6 receptors on the bipolar cell.
9. More activation of mGluR6 receptors on the bipolar cell leads to hyperpolarization of the bipolar cell.
10. Hyperpolarization of the bipolar cell leads to less release of glutamte from the bipolar cell.
11. Less release of glutamate form the bipolar cell leads to less binding of glutamate onto AMPA/NMDA receptors on the retianl ganglion cell.
12. Less activation of AMPA/NMDA receptors on the retinal ganglion cell leads to less firing of action potentials.
Off center On Surround
Direct Pathway
1. Light onto the center of the receptive field hyperpolarized the photoreceptor cell
2. The photoreceptor cell releases less glutamate
3. Less glutamate binds to the AMPA/Kainate receptor on the bipolar cell leading to hyperpolarization of the bipolar cell.
4. Hyperpolarization of the bipolar cell leads to less glutamate release by the bipolar cell.
5. Less glutamate release from the bipolar cell leads to less binding of glutamate to AMPA/NMDA receptors on the retinal ganglion cell.
6. Lesactivation of AMPA/NMDA receptors on the retinal ganglion cell leads to less firing of action potentials
Indirect Pathway
1. Light onto the surround of the receptive field hyperpolarizes the photoreceptor cell.
2. Hyperpolarization of the photoreceptor cell leads to less release of glutamate onto horizontal cells.
3. Less glutamate binds to the horizontal cell leading to hyperpolarization.
3. Hyperpolarization of horizontal cells leads to less release of GABA onto the center photoreceptor cell.
4. Less activation of GABA receptors on the center photoreceptor cell leads to depolarization of the center photoreceptor cell.
5. Depolaraztion of the center photoreceptor cell leads to more glutamate release from the center photoreceptor cell.
6. More activation of AMPA/Kainate receptors on the bipolar cell leads to depolarization of the bipolar cell.
7. Depolarization of the bipolar cell leads to more release of glutamate from the bipolar cell.
8. More release of glutamate from the bipolar cell leads to more binding of glutamate onto the AMPA/NMDA receptors on the retinal ganglion cell.
9. More activation of AMPA/NMDA receptors on the retinal ganglion cell leads to more firing of actional potentials.
Thank You
Explanation / Answer
There is no such error in the answer.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.