Based on the given data, KTKEGV refers K = Lysine T = Threonine E = Glutamic aci
ID: 55775 • Letter: B
Question
Based on the given data, KTKEGV refers
K = Lysine
T = Threonine
E = Glutamic acid
G = Glycine
V= Valine
Among these amino acids, Lysine and Glutamic acid are electrically charged amino acids and Glycine, valine are non-polar amino acids. Threonine alone is a polar amino acid. Therefore, the structure is the given Hexapeptide is as follows:
NH2-Lysine-threonine-lysine-glutamic acid-glycine-valine-COOH
What do you notice about its structure? Is it very hydrophobic, hydrophilic? Would you expect to find this fragment on the surface of the protein or buried deep inside?
Explanation / Answer
The given peptide is hydrophilic in nature, as four of the six amino acids are hydrophilic. This fragment is present on the surface of the protein. The amino acids NH2-lysine-threonine-lysine-glutamic acid- lie above the surface, while the amino acids -glycine- on the surface, and amino acid -valine-COOH within the membrane being hooked.
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