Proteoglycans are part of the extracellular matrix; they provide structure, visc

Question

Proteoglycans are part of the extracellular matrix; they provide structure, viscosity and lubrication, and adhesiveness. They are composed of proteins conjugated to carbohydrate components called glycosaminoglycans. The glycosaminoglycan component makes up the majority of the mass of a proteoglycan (a) Which of the following are possible components of glycosaminoglycans? Select all that apply. N-acetylglucosamine BD-fructofuranose amylose uronic acid (b) Determine which of the following statements about glycosaminoglycans are true. There is more than one true statement; select all the true statements The amino groups of the amino sugar derivatives provide a positive charge that offsets the negative charges from the sulfate or carboxylate groups. Cellulose is an example of a glycosaminoglycan. Because glycosaminoglycans consist of only two residues, they generally have low molecular weights. Chondroitin sulfate and heparin are examples of glycosaminoglycans Glycosaminoglycans are heteropolysaccharides composed of repeating disaccharide units

Explanation / Answer

a) ans = N-acetylglucosamine and uronic acid

Glycosaminoglycans consists of an amino sugar (N-acetylglucosamine) along with uronic acid.

b) Glycosaminoglycans are heteropolysaccharides having high molecular weights. The repeating units are disaccharide units.

No positive will be provided by amino groups of amino sugar derivatives in Glycosaminoglycans.

    Cellulose is not a Glycosaminoglycan. Cellulose is a homopolysaccharide.

Therefore,

ans =    - Glycosaminoglycans are heteropolysaccharides composed of disaccharide units.

            - Chondroitin sulfate and heparin are examples of Glycosaminoglycans.

   

     

            

            

      

            

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