For a situation where the fitness of a heterozygote is less than that of either

Question

For a situation where the fitness of a heterozygote is less than that of either homozygote, give the proportion of alleles A1 and A2 in the populations over the next FIVE generations in the future if:

p = 0.65, q = 0.35, s1 = 0.02 and s2 = 0.9

(remember, in this case the relative fitness of the homozygotes will be 1 + s. The initial conditions you are given here are considered generation zero)

Provide a graph of the proportions of A1 and A2 in the population against time (measured in generations)

Explanation / Answer

Genotypes A1 and A2, with frequencies p=0.65 q= 0.35

s1 and s2 are selection coeeficients.

Selection coeeficient refers to the reduction in relative fitness therefore genetic contribution to future generation of one genotype than other.

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