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uppose the interference value (I) between loci A and B is the same as the interf

ID: 55304 • Letter: U

Question

uppose the interference value (I) between loci A and B is the same as the interference between loci B and C, and the order of the loci on the same autosome is A-B-C. If I = 0.05, then a recombination between loci A and B implies:
A. the recombination fraction between A and B is equal to the recombination fraction between B and C.
B. a recombination between loci B and C has an apporixmately 5% probability
C. a recombination between loci B and C has a near 100% possibility
D. a recombination between loci B and C has an approximately 50% probability
E. a recombination between loci B and C has a near 0% probability

What should be the answer

Explanation / Answer

E. a recombination between loci B and C has a near 0% probability

Interference is calculated from the coefficient of coincidence. Interference = 1- c.o. c

Thus, the coefficient of coincidense in this case = 0.95

Coefficient of coincidence is = actual double recombinant frequency / expected double recombinant frequency

Double recombination occurs between A and C, as the gene order is A-B-C, but does not occur between B and C.