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1.) In tomato plants, for three traits: solid leaves ( M_ ) are dominant to mott

ID: 54968 • Letter: 1

Question

1.) In tomato plants, for three traits: solid leaves (M_) are dominant to mottled leaves (mm), normal height (D_) is dominant to dwarf height (dd), and smooth skin (P_) is dominant to peach skin (pp). Suppose that you perform the following cross: MmDdPp x mmddpp. You plant 1000 tomato seeds resulting from the cross, and get the following results:

Use this information to complete the following linkage map. A, B, and C are distances, and “gene 1” and “gene 2” are genes. Gene m has already been placed on the linkage map.

A =

B =

C =

gene 1 =

gene 2 =

Choose from the answer choices below:

a) 5 cM

b) 7 cM

c) 12 cM

d) 15.8 cM

e) 17 cM

f) 17.4 cM

g) p

h) d

2.) In chupacabras, brown (B) fur is dominant to black (b), and red eyes (G) are dominant to green (g). A chupacabra that is homozygous for black fur and green eyes mates with one that is homozygous for brown with red eyes. The F1 are then mated in a series of testcrosses, producing the following progeny. Do the genes assort independently? Round your expected values AND your final answer to one decimal place. For example, 321.12345 = 321.1. R

a) Chi-square value =

b) Do the genes assort independently ? (type "yes" or "no")

Phenotype Number Brown, Red eyes 185 Brown, Green eyes 164 Black, Red eyes 162 Black, Green eyes 179 Total 690

Explanation / Answer

1. The cross is:

MmDdPp..................................... .......................................................x...............................................mmddpp.

Gametes: ..MDP,mdp,Mdp,MDp,MdP,mDP,mdP,mDp...........................................................mdp

F1: MmDdPp : solid leaves, normal height, smooth skin = 420

mmddpp: mottled, dwarf, peach = 416

Mmddpp: solid, dwarf, peach = 52

MmDdpp: solid, normal, peach = 21

MmddPp: solid, dwarf, smooth = 2

mmDdPp: mottled, normal, smooth = 62

mmddPp: mottled, dwarf, smooth= 23

mmDdpp: mottled, normal, peach = 4

·         Largest number of offsprings: parental genotype= (1) solid leaves, normal height, smooth skin = 420 &

(2) mmddpp: mottled, dwarf, peach = 416

·         Smallest number of offsprings: double cross-over leading to these genotypes = (1) MmddPp: solid, dwarf, smooth = 2 & (2) mmDdpp: mottled, normal, peach = 4

ORDER of gene: m.d.p (so no need to change the order of genes in the representation of genotype in the F1)

Now, Distance between m & d = ( Single crossing over between m & d + Double crossing over )/ Total =

(52+62) + (2+4) / 1000 = 120/1000 = 0.12 = 12 cM

Now, Distance between d & p = ( Single crossing over between d & p + Double crossing over )/ Total =

((21+23)+(2+4))/1000=50/1000= 0.05 = 5 cM

Distance between m & p = ( Single crossing over between m & p + 2 X Double crossing over )/ Total =

(21+23+52+62)+2X(2+4)/1000 = 170/1000 = 0.17= 17 cM

ANSWER: A = 12 cM

B = 5 cM

C = 17 cM

gene 1 = d

gene 2 = p

2. In chupacabras, brown (B) fur is dominant to black (b), and red eyes (G) are dominant to green (g).

A chupacabra that is homozygous for black fur and green eyes mates with one that is homozygous for brown with red eyes.

Hence, the cross is : bbgg................X......................................BBGG

gametes:........................bg...............................................BG

F1:.............................................BbGg ( brown fur + red eyes)

Now, the F1 is test-crossed.

BbGg....................................................................X.....................................bbgg

gametes: BG,Bg, bG,bg..............................................................bg

F2:...........BbGg( brown fur, red eye)...........Bbgg(brown fur, green eye)..........bbGg( black fur, red eye).............bbgg (black fur, green eye)

Hence all the four phenotypes appear in 1:1:1:1 ratio

Hence out of 690 progenies, each phenotype's expected appearance should be = 690/4 = 172.5

NULL HYPOTHESIS: Gene assortment occurs independently.

PHENOTYPE

Observed number (O)

Expected number(E)

(O-E)2/E

Brown, red eyes

185

172.5

0.905

Brown, green eyes

164

172.5

0.418

Black, red eyes

162

172.5

0.639

Black, green eyes

179

172.5

0.326

Chi square value = 0.905+ 0.418+ 0.639+ 0.326 = 2.288 = 2.3 (rounded upto 1 decimal place)

Degrees of freedom = (k-1) – (r-1) where k is number of phenotype & r is number of allele

Compare chi square value for the relevant degree of freedom from the standardised chart of chi square values; if chi square value ( 2.3) is less than tabulated value, null hypothesis holds true.

Hence gene assortment occurs independently.

PHENOTYPE

Observed number (O)

Expected number(E)

(O-E)2/E

Brown, red eyes

185

172.5

0.905

Brown, green eyes

164

172.5

0.418

Black, red eyes

162

172.5

0.639

Black, green eyes

179

172.5

0.326