1. The committed step of a metabolic pathway is often inhibited by the final pro
ID: 545486 • Letter: 1
Question
1. The committed step of a metabolic pathway is often inhibited by the final product of the pathway. This type of inhibition is an example of inhibition. 2. Metal ions often play different roles in enzymes. For the following enzymes, name the metal ion involved, describe how it is bound to the enzyme and whether it plays a role in catalysis. a. Carbonic anhydrase b. Aspartate transcarbamoylase 3. Two enzymes that differ in amino acid sequence, and yet catalyze the same reaction are called -1.4 +ha einhctrate saturation curve to the . .---Explanation / Answer
1. feedback inhibition.
2. a. metal ion is zinc.
zinc role in carbonic anhydrase is to facilate the water moelcue to create a proton H+and a nucleophilic hydroxide ion.The nucleophilic water molecule attack the carbonyl gorup of carbon dioxide to convert it into bicarbonate.
b. metal ion involved in aspartate transcarbomylase is Mg+2( magnesium)
3. Isozymes or Isoenzymes
Isoenzymes are enzymes that catalyze the same reaction yet differ in amino acid sequence.
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