Transcription of cAMP response element containing genes induced by CREB requires

Question

Transcription of cAMP response element containing genes induced by CREB requires which of the following steps?

Nuclear export of CREB and CBP following methylation

Phosphorylation of CREB serine 133, recruitment of CBP, and acetylation of chromatin.

Ubiquitination of CREB arginine 47, recruitment of NCOR1, and Histone 4 lysine 27 methylation

Nuclear export of CREB and CBP following methylation

Phosphorylation of CREB serine 133, recruitment of CBP, and acetylation of chromatin.

Ubiquitination of CREB arginine 47, recruitment of NCOR1, and Histone 4 lysine 27 methylation

Explanation / Answer

Transcription of cAMP response element containing genes induced by CREB requires Phosphorylation of CREB serine 133, recruitment of CBP, and acetylation of chromatin

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