18.03 1. Alu elements are part of which type of non-coding transposable DNA sequ
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Question
18.03
1.
Alu elements are part of which type of non-coding transposable DNA sequence (all types of transposons and mobile genetic elements together comprise 45% - nearly half of our genome!) ?
A. segmental duplications
B. dead transposons
C. SINEs
D.LTRs
E. LINEs
2.
The human genome contains fewer genes than
A. bacteria do.
B. fruit flies do.
C. nematodes do.
D. mice do.
E. rice does.
3.
The coding region of a gene between a "start" and a "stop" codon is referred to as the
A. LINE Long Interspersed Element.
B. PCR Polymerase Chain Reaction.
C. ORF Open Reading Frame.
D. SSR Simple Sequence Repeat.
E. STS Sequence Tagged Site.
4.
Single copy genes silenced by mutation are called
A. heterochromatin.
B. pseudogenes.
C. RFLPs.
D. homeogenes.
E. retrogenes.
5.
The number of proteins produced by the human genome is greater than the number of genes because of
A. alternative splicing of mRNA.
B. EST amplification.
C. LTRs.
D. pseudogenes that lead to families of proteins.
E. transposable elements.
6.
Which of the following is not an example of noncoding DNA?
A. heterochromatin
B. SSRs
C. pseudogenes
D. retrotransposons
E. tandem clusters
7.
Which of the following is the same as heterochromatin?
A. structural DNA
B. LINE
C. segmental duplication
D. ALU
E. pseudogenes
8.
The tendency of single genes not to randomize during meiotic division is called
A. genome conservation.
B. transcription equilibrium.
C. linkage disequilibrium.
D. genetic stabilization.
E. nondisjunction.
9.
The primary function of a BLAST search is
A. to cause the transposition of genes from one place in the genome to another more preferred location.
B. to identify homology between sequences from different organisms, and make inferences about similarity of function of resultant proteins.
C. to blow up cells.
D. to sequence genes completely, with all controlling elements.
10.
Sites where individuals differ by a single nucleotide are called
A. SSRs.
B. SNPs.
C. LINEs.
D. RFLPs.
E. SINEs.
11.
How much of the human genome is made up of exons (protein encoding portions of genes)?
A. 45%
B. 21%
C. 98.5%
D. 1.5%
E. 5%
12.
Match the following
1. The production of more than one protein from a single gene.
2. Ancient transposable elements, 6000bp long, that make up 21% of the human genome, and carry with them all the "equipment" needed for transposition.
3. A one- to six-nucleotide sequence repeated thousands of times, making up 3% of the human genome.
4. The Alu element is one of these, which represents 10% of the human genome.
5. Bits of DNA that are able to move from one location on a chromosome to another.
6. The tendency for genes not to be randomized, which can be used to map their locations.
7. Produced from one or both ends of short sections of sequenced cDNAs made from expressed mRNA.
8. Regions of chromosomes that are not being exchanged by genetic recombination.
9. The conversion of basic sequence information into a form that can be recognized based on landmarks.
10. Retrotransposons that make up 8% of the human genome which contain repeat motifs at each end.
11. The coding region of a gene that begins with a start codon and ends with a stop codon.
12. Sites in the DNA sequence of a population of individuals that differ by only a single nucleotide.
A. simple sequence repeats (SSRs)
B. transposable elements
C. long terminal repeats (LTRs)
D. open reading frame (ORF)
E. haplotypes
F. annotation
G. long interspersed elements (LINES)
H. alternative splicing
I. short interspersed elements (SINES)
J. linkage disequilibrium
K. single nucleotide polymorphisms (SNPs)
L. expressed sequence tag (EST)
Explanation / Answer
1 . Ans C SINE 11. D 1.5 percent
2. A bacteria
3.ans C open reading frame ORF
4.ans heterochromatin
5 ans d pseudogenes that lead to no translation
6. Ans B ssr
7 ans structural dna A
8 ans D
9 ans B
10ans SNP B
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