A neural cell you isolate from Spongebob\'s pal Squidworth with an intracellular

Question

A neural cell you isolate from Spongebob's pal Squidworth with an intracellular Cl^- ion concentration of 55 mM is placed in a solution containing 560 mM Cl^- (roughly approximating physiological conditions). The cell membrane potential is -60 millivolts (also standard for squid). What is the DeltaGinward value associated with transporting Cl^- ions into the cell? Does this value indicate that inward transport is passive, or is active transport required? R= 1.987 cal/mol, T= standard room temperature 298 K, F = 23,062 cal/mol-V. A neural cell you isolate from Spongebob's pal Squidworth with an intracellular Cl^- ion concentration of 55 mM is placed in a solution containing 560 mM Cl^- (roughly approximating physiological conditions). The cell membrane potential is -60 millivolts (also standard for squid). What is the DeltaGinward value associated with transporting Cl^- ions into the cell? Does this value indicate that inward transport is passive, or is active transport required? R= 1.987 cal/mol, T= standard room temperature 298 K, F = 23,062 cal/mol-V. A neural cell you isolate from Spongebob's pal Squidworth with an intracellular Cl^- ion concentration of 55 mM is placed in a solution containing 560 mM Cl^- (roughly approximating physiological conditions). The cell membrane potential is -60 millivolts (also standard for squid). What is the DeltaGinward value associated with transporting Cl^- ions into the cell? Does this value indicate that inward transport is passive, or is active transport required? R= 1.987 cal/mol, T= standard room temperature 298 K, F = 23,062 cal/mol-V.

Explanation / Answer

Ginward = RT ln [Cl-]inside / [Cl-]outside + ZFVm
R = 1.987 cal/mol ; T = 298K ; F = 23062 cal/mol V
Z = 1 ; Vm = -60mV = -0.06 V
Ginward = 1.987 * 298 ln (55/560) + 1*(-0.06)*23062
Ginward = -2757.8097 cal/mol = -2.7578 Kcal/mol
Since Ginward is negative so the ions are moving down (releasing energy)
it indicates passive transport .

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