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1.) PLEASE ANSWER ALL QUESTIONS IF POSSIBLE!!! Assume that a disease in humans i

ID: 52915 • Letter: 1

Question

1.) PLEASE ANSWER ALL QUESTIONS IF POSSIBLE!!!
Assume that a disease in humans is caused by the dominant autosomal mutation with 80% penetrance. A person who is heterozygous for this mutation mates with a person who is homozygous for the normal allele. What is the probability that their first child will have the disease?  
.8    .5   .4 .2

This is an example of incomplete penetrance

the genotype of the pink flowers is Rr

the R allele is showing incomplete dominance

none of the above - they are ALL true

a.

This is an example of incomplete penetrance

b.

the genotype of the pink flowers is Rr

c.

the R allele is showing incomplete dominance

D.)

none of the above - they are ALL true

Explanation / Answer

4. Answer Option D. Ratio will be 9:3:4.

Normal ratio is 9:3:3:1, but here last two will be yellow. So we add them and get 9:3:4.

1. Answer Option D. Expected % for child to be diseased is 25 % or .25. And penetrance is 80%. So probability = 0.25 * 0.8 = 0.2.

3. Answer Option E. Since its 5 alleles, number of possible genotypes will be more than 25. So this is the best suitable answer. Formula to find number of Genotypes is 3^n, where n = number of allele - 1.