What cascade(s) is/are unique to apoptosis that is/are not otherwise found in HE

Question

What cascade(s) is/are unique to apoptosis that is/are not otherwise found in HER1-dependent cell proliferation?

E. (b) & (c)

Tarceva (aka Erlotinib) inhibits the binding of GRB2 to EGFR, but also prevents their desensitization. What is Tarceva’s direct mechanism of action?

E. Inhibits RAF activity.

Can someone also answer my 2-3 previous questions?! Please and thank you!

A. Kinase cascade B. Transcription factor cascade C. Caspase cascade D. (a) & (c)

E. (b) & (c)

Tarceva (aka Erlotinib) inhibits the binding of GRB2 to EGFR, but also prevents their desensitization. What is Tarceva’s direct mechanism of action?

A. Inhibits SOS GEF activity. B. Prevents AP2 from binding to Clathrin. C. Inhibits MAPK activity. D. Inhibits EGFR Kinase activity.

E. Inhibits RAF activity.

Can someone also answer my 2-3 previous questions?! Please and thank you!

%Activity or %Activity or %Activity or % Maximal Fluorescence at 527 nm- % Maximal Fluorescence at 527 nm % Maximal Fluorescence at 527 n Add PDGF Remove PDGF 100 Time Add PDGF Remove PDGF 00 Time Add PDGF Remove PDGF 100 Time

Explanation / Answer

D) is correct answer ie kinase cascade and caspase cascade are unique in apotosis that are not otherwise present in HER1-dependent cell proloiferation.

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