You have been asked to measure the partition coefficient of drug candidates. All
ID: 510646 • Letter: Y
Question
You have been asked to measure the partition coefficient of drug candidates. All the procedures you have found require that the drug candidate absorb light in the UV-visible range when dissolved in water. What is the absorbance used for?
a. The absorbance will be used to identify the drug.
The absorbance will be used to measure the concentration of the drug.
c. The absorbance will be used to detect impurities.
d. The absorbance will be used to ensure that the drug is not phototoxic to people.
a. The absorbance will be used to identify the drug.
Explanation / Answer
Both a and b are correct. Absorption Spectrophotometry can be used to identify compounds based on their wavelength maxima and also beers law can be used to calculate their concentration.
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