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Urea is a waste product of amino acid metabolism, however, it is also critical f

ID: 49546 • Letter: U

Question

Urea is a waste product of amino acid metabolism, however, it is also critical for normal kidney function for which of the following reasons?

Along with potassium, urea is the main solute used to establish the osmotic gradient of the renal medulla, increasing water reabsorption by osmosis.

Along with sodium, it is secreted by the collecting duct and prevents water reabsorption into the urine.

It is reabsorbed at the collecting duct and, along with sodium, aids in establishing the osmotic gradient in the renal medulla, increasing water reabsorption by osmosis.

High concentrations of urea in the proximal and distal tubules establishes an osmotic gradient that causes water reabsorption at the tubules.

Urea is required for amino acid metabolism, without it, proteins could not be broken down into monomer subunits, causing kidney failure.

Along with potassium, urea is the main solute used to establish the osmotic gradient of the renal medulla, increasing water reabsorption by osmosis.

Along with sodium, it is secreted by the collecting duct and prevents water reabsorption into the urine.

It is reabsorbed at the collecting duct and, along with sodium, aids in establishing the osmotic gradient in the renal medulla, increasing water reabsorption by osmosis.

High concentrations of urea in the proximal and distal tubules establishes an osmotic gradient that causes water reabsorption at the tubules.

Urea is required for amino acid metabolism, without it, proteins could not be broken down into monomer subunits, causing kidney failure.

Explanation / Answer

High concentrations of urea in the proximal and distal tubules establishes an osmotic gradient that causes water reabsorption at the tubules.

A higher concentration gradient will be established for ammonia at the late proximal tubule. This causes passive reabsorption of urea down its concentation gradient and alsopromotes waterreabsorption in this region. This is an adative mechanism for water conservation in terrestrial animals.

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