is a serious condition resulting from the ingestion of lead in other environment
ID: 483665 • Letter: I
Question
is a serious condition resulting from the ingestion of lead in other environmental sources. It affects the central nervous system, leading to a variety of symptoms such as distractibility, lethargy, and loss of motor coordination. Lead poisoning is treated with chelating agents, substances that bind to metal ions, allowing it to be eliminated in the urine. A modern chelating agent used for this purpose is succimer, C_4H_6O_4S_2. Suppose you are trying to determine the appropriate dose for succimer treatment of lead poisoning. What minimum mass of succimer (in mg) is needed to bind all of the lead in a patient's bloodstream? Assume that patient blood lead levels are 41 mu g/dL that total blood volume is 5.0 L, and that one mole of succimer binds one mole of lead.Explanation / Answer
Given:
Blood lead level: c = 41µgdL{-1} = 0.41 mgL{-1}
Blood volume: V = 5.0L
Atomic Mass Lead: M(Pb) = 207.2gmol{-1}
Molecular Mass Succimer:
M(C4H6O4S2) = 4 × 12.01 + 6 × 1.008 + 4 × 16.00 + 2 × 32.1 gmol{-1} = 182.(288) gmol{-1}
Stiochiometry: 1 Pb : 1 C4H6O4S2
Succimer Needed: cVM(C4H6O4S2)/M(Pb) = 0.41mgL{-1} × 5.0L × 182.(288)gmol{-1} / 207.2gmol{-1}
= 1.8 0(795)mg
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