Progression through and control of cell cycle involve: 1)Cyclins binding to Cdk
ID: 47384 • Letter: P
Question
Progression through and control of cell cycle involve:
1)Cyclins binding to Cdk because without cyclin binding, a cell-cycle checkpoint will be activated
3)Changes of the Cdk activity, because Cdk degradation leads entry into the next phase of the cell cycle.
4)The binding of a cyclin to Cdk is required for Cdk enzymatic activity and cyclin levels change during the cycle
5)The Cdks activate the cyclins and CdK levels change during the cycle
2)Cyclins binding to CDk,because cyclins inhibit Cdk activity until the appropriate time in the cell cycle.Explanation / Answer
In eukaryotic cell cycle, cyclins and CDKs play an important role in regulation. Cyclins form regulatory subunits and CDKs form catalytic subunits. CDKs cannot function in the absence of cyclins. CDKs perform phosphorylation which activates or deactivates target proteins that mediate next phase of cell cycle. CDKs are continuously present in the cell but cyclins are produced at specific stage of cell cycle. The production of cyclins is affected by several signals.
The correct option for the given question is 4
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