1) Mutation of the gene encoding the E. coli lac repressor protein, so that the

Question

1) Mutation of the gene encoding the E. coli lac repressor protein, so that the protein cannot bind to allolactose would lead to what kind of gene expression pattern phenotype for the lac operon, relative to the wild type allele?

A. Cis dominant                   B. Cis recessive           C. Trans dominant          D. Trans recessive

2) Mutation of the gene encoding the E. coli trpR protein so that the protein cannot bind to tryptophan would lead to what kind of gene expresison pattern phenotype for the trp operon, relative to the wild type allele?

A. Cis dominant          B. Trans dominant          C. Trans recessive

3) Deletion of the 3' UTR of lin-14 mRNA would lead to what kind of gene expression pattern phenotype relative to wild type allele?

A. Cis dominant                  B. Cis recessive           C. Trans dominant          D. Trans recessive

4) Which enzyme cleaves pre-miRNAs to generate miRNA/miRNA* duplexes?

A. Dicer                B. Slicer                 C. Drosha                    D. RISC

5) Histone H1 is required for the formation of the:

A. Nucleosome     B. 10nm fiber form of chromatin     C. 30nm fiber form of chromatin     D. All of the above

6) The 5' splice site of a nucler group II pre-mRNA intron is boudn by which snRNP at the earliest stage of splicing reaction?

A. U1               B. U2             C. U5               D. U6

7) Overexpression of the cro gene of the bacteriophage lambda would favor which pathway?

A. Lysis              B. Lysogeny

8) Which DNA repair mechanism is invovled in repair of DNA abnormalities resulting from replication slippage?

A. Mismatch repair         B. Base excision repair         C. Nucleotide excision repair         D. Recominbation-based repair

9) What is the name of the transcriptional repressor protein which is cleaved and inactivated in the bacterial DNA damage response?

A. RecA       B. LexA      C. RexA    D. DinI

IF YOU DO NOT KNOW DO NOT ANSWER!!!! I need these points, thank you! :)

Explanation / Answer

1. a cis dominant

2. trans recessive

3. cis dominant.

4. dicer

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