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1) Mechanisms by which antibiotics kill or inhibit microbial growh are: )Inhibit

ID: 132597 • Letter: 1

Question

1) Mechanisms by which antibiotics kill or inhibit microbial growh are: )Inhibition of cell wall synthesis b) Injury to cell membrane Inhibition of protein synthesis d) Inhibition of DNA or RNA syntheis e) Allof the above 2) The semisynthetic methicillin has the advantage of: Being broad spectrum b Being inactivated by penicillinase only on prolonged usage Not being affected by penicillinase d) All of the above )None of the above Which of the following interfere with cell wall synthesis? bTetracyclines c Penicillin d) Bacitracin ) Only C and D above A rare but serious complication of chloramphenicol treatment is Kidney damage Deafness due to damage to eighth cranial nerve Anemia due to suppression of bone marrow cells Anemia due to destruction of circulating red blood cells None of the above b) The development of drug resistance in a microorganism may be due to: aAbility of the organism to destroy the antibiotic b Mutation that allows the organism to by-pass the sensitive step c)Sporulation d) All of the above e) Only A and B above 6 The synthesis of vitamins B and K by enteric bacteria provides an example b) Symbiosis cOpportunism d) nfection Synergestic effect

Explanation / Answer

1)e)all of the above- as it differs by antibiotics in which some will inhibit DNA replication,transcription,some inhibit cell wall synthesis ,some protein synthesis.

2)c)not being affected by penicillinase

3)e)c and d above as both penicillin and bacitracin interefere with cell wall synthesis.

4)c)anemia due to suppression of bone marrow cells

5)b(mutation that allows the microorganism to by pass the sensitive step.

6)a)commensalism as only the enteric bacteria has the benefits by secreting vitamins.