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7) A mutation occurs in a eukaryotic gene that causes the creation of a stop cod

ID: 42817 • Letter: 7

Question

7) A mutation occurs in a eukaryotic gene that causes the creation of a stop codon in the 5' UTR region of the mRNA. As a result, you would expect: a) this mRNA transcript will not be translated at all this mRNA transcript will be partially translated, only up until the point where the mutation-induced stop codon is encountered by the ribosome this mRNA will be translated normally, this mutation will not affect gene expression this gene will not even be transcribed properly if a stop codon occurs in the 5' UTR

Explanation / Answer

A mutation occurs in a eukaryotic gene that each causes the creation of a stop codon in the middle of the 5' UTR region of the mRNA. As a result, you would expect:

a) this mRNA transcript will not be translated at all
b) this mRNA transcript will be partiall translated, only up until the point where the mutation-induced stop codon is encountered by the ribosome
c) this mRNA will be translated normally, this mutation shoould not effect gene expression
d) this gene will not even be transcribed properly if a stop codon occured in the 5' UTR

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