Match the following translation factors with their function(s): ____binds to the

Question

Match the following translation factors with their function(s):

       ____binds to the A site when a stop codon is present                                   A. IF2

       ____keeps the small subunit from binding to the large subunit                     B. RF1

       ____brings the charged tRNA to the A site                                                    C. EFG

       ____allows GDP to be replaced with GTP on another factor                         D. eIF4F

       ____brings the initiator tRNA to the P site E. EFTs

       ____helps the mRNA bind to the small subunit                                              F. IF1

       ____moves the tRNA and the mRNA codon from the A site to the P site     G. EFTu

       ____binds to the 5'-methyl-G-cap and the small subunit                               H. IF3

Also, which two translation factors in the above question are responsible for setting the reading frame of the mRNA in prokaryotes and eukaryotes, but do it with different mechanisms?

Explanation / Answer

binds to the A site when a stop codon is present - RF1

keeps the small subunit from binding to the large subunit - IF3

brings the charged tRNA to the A site - EFTu

allows GDP to be replaced with GTP on another factor -EFTs

brings the initiator tRNA to the P site - IF2

helps the mRNA bind to the small subunit - .IF3

moves the tRNA and the mRNA codon from the A site to the P site- EFG

binds to the 5'-methyl-G-cap and the small subunit - eIF4F

IF1 and IF3 are responsible for setting the reading frame of the mRNA

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