Bcl-2 is \"pro-survival\" because: A. it activates the PI3K/Akt pathway. B. it l
ID: 41088 • Letter: B
Question
Bcl-2 is "pro-survival" because:
A.
it activates the PI3K/Akt pathway.
B.
it lies downstream of various pro-apoptotic signals.
C.
it contains several BH (Bcl homology) domains.
D.
its normal cellular function is to initiate the formation of apoptosomes.
E.
its normal cellular function is to inhibit the formation of Bax/Bak channels within the mitochondrial outer membrane.
A.
it activates the PI3K/Akt pathway.
B.
it lies downstream of various pro-apoptotic signals.
C.
it contains several BH (Bcl homology) domains.
D.
its normal cellular function is to initiate the formation of apoptosomes.
E.
its normal cellular function is to inhibit the formation of Bax/Bak channels within the mitochondrial outer membrane.
Explanation / Answer
its normal cellular function is to inhibit the formation of Bax/Bak channels within the mitochondrial outer membrane.
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