Three genes control the production of tail structures in dogs. The wag1 gene pro

Question

Three genes control the production of tail structures in dogs. The wag1 gene promotes the production of tail structures. However, the brkn gene inhibits wag1 activity. Another gene, ntrdr, stimulates activity of the brkn gene. Put these genes in order in a developmental pathway. Use arrows and t-bars between the genes as appropriate.

Write out the Pathway.

You conducted an experiment in which you knocked out the activity of the ntrdr gene in early embryological development. Will tail structures be produced by this animal?

Yes

No

Explanation / Answer

Different genes present in the experiment - Wag-1 - promotes production of tail structures

brkn gene inhibits Wag-1 -when wag 1 is inhibited, there is no tail formation.

ntrdr gene stimulates the activity of brkn gene.- ntrdr gene activates the brkn gene thus this inturn inhibits Wag-1 gene, thus inhibiting the tail formation.

2. The ntrdr gene activates the brkn gene and this inturn inhibits the wag-1 gene that is actually responsible for tail formation. on knocking out ntrdr gene, gene brkn is inactive thus allows the expression of the Wag-1 gene allowing tail growth in dogs.

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