1. How are the endergonic reactions of thefirst phase of glycolysis coupled to t
ID: 3771 • Letter: 1
Question
1. How are the endergonic reactions of thefirst phase of glycolysis coupled to the hydrolysis of ATP, whichis exergonic? How are the exergonic reactions of the second phaseof glycolysis coupled to the endergonic synthesis of ATP andNADH? 2. In what ways is the inner mitochondrialmembrane essential to the coupling of electron transport and ATPsynthesis? Could the membrane carry out its function if its lipidbilayer were readily permeable to hydrogen ions (protons)? 1. How are the endergonic reactions of thefirst phase of glycolysis coupled to the hydrolysis of ATP, whichis exergonic? How are the exergonic reactions of the second phaseof glycolysis coupled to the endergonic synthesis of ATP andNADH? 2. In what ways is the inner mitochondrialmembrane essential to the coupling of electron transport and ATPsynthesis? Could the membrane carry out its function if its lipidbilayer were readily permeable to hydrogen ions (protons)?Explanation / Answer
In the initial stages of Glycolysis, the cell needs to use ATP tofix a phosphate to glucose (creatingglucose-6-phosphate). When the phosphate is released from ATP (exergonic) energy isreleased, it is an endergonic reaction, because the Glucose-6Pmolecule absorbs the energy of a phosphate. The second part of question one is essentially the same, butbackwards.
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