Fill in the blanks: During SRP-mediated secretion, an N-terminal _____ found on

Question

Fill in the blanks:

During SRP-mediated secretion, an N-terminal _____ found on a newly synthesized or _____ polypeptide is recognized by SRP, which is a complex between a protein called ______ and a sRNA called _____. The binding of SRP to the SS causes the ribosome to stall and the entire complex is moved closer to the cell membrane. Since the process of synthesizing the protein and its insertion into the membrane is coupled, this entire process is called _____. Some proteins can insert themselves into the membrane without the assistance from other proteins. However, in other situations, the SRP complex delivers the growing protein to a membrane-associated shuttle protein called _____, which brings the SRP-protein complex called the ____ translocon.

Explanation / Answer

1. peptide or amino acids

2. nascent

3.  Ffh, Fifty-four homolog (in prokaryotes).

4.   4.5S RNA

5. Co-translational translocation

6. SRP receptor

7. ER

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