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ot transmitted without pub NAME SECTION UNIT QUIZ: Critical Thinking and Applica

ID: 3523021 • Letter: O

Question

ot transmitted without pub NAME SECTION UNIT QUIZ: Critical Thinking and Application Questions 5 1 The condition Marfan fibers. Predict the potential elastic fibers are found. How would defective elastic fibers impair the functions of thoe organs and tdisu) syndrome results from the production of abnormal dlastin, the main protcin component ot consequences of defective elastic fbers.(Hint: Consider the organs and tissues in which Other diseases, called collagen vascular diseases, impact the protein collagen, the main component of collagen ibers Predict the possible consequences of defective collagen fbers on specific organs and tissues 3 How would the effects of a collagen vascular disease that affected only the collagen in reticular bers differ from the ef- fects seen with question two? Why? would provide an articular surface (fi.e, the carnilage in joints) that is as smooth as the original hyaline cartilage Why or why not? 4 The formation of ibrocartilage is a common response to injury of hyaline cartilage. Do you think that fbrocarilage Histology Unit 5

Explanation / Answer

2. Defective collagen fibres can affect the skin, lungs,,bones,ligaments,muscles,heart,digestive tract.. it may cause rhematoid arthritis at bones and joints.. scleroderma at skin,heart and lungs...temporal arteritis at arteries..it may also causes lupus..

3. In reticular fibres the collagen found is of third type and in others like skin ,artery walls etc mostly type one collagen is found.... In reticular fibre collagen defect the disorder is mostly said to be ehlers danlos syndrome amd the gene responsible is COL3A1 while in 2nd question the genes involved are basically COL1A1 AND COL1A2.... In reticular fibres the collagen is of granulation tissue which is priduced by the young fibroblastf before the collagen type 1.

4.No, beacuse hyaline cartilage's smooth appearance is due to the absence of protein fibres in it..whereas fibrocartilage is abundant in protein fibres which does not giv it a smooth appearance..