Endocrine System Helen is a 45-year-old housewife, lately she\'s noticed that sh
ID: 3522642 • Letter: E
Question
Endocrine System Helen is a 45-year-old housewife, lately she's noticed that she has been losing weight but maintaining her caloric intake and still going for her 2 powerwalks a week, although she feels like she needs to start running as when she gets home she is full of beans. She has also been increasingly irritated with her husband Timothy who has been putting the electric blanket on in bed when she is already overheating Helen goes to her local clinic to see Dr. Dresden, who notes that her body temperature is above average and she has in fact lost 10 kg since her regular check-up 4 months ago. Dr. Dresden orders a blood test to check Helen's thyroid hormone levels T4 concentration 15.2 ug/d (N-4.5-12.5), T3 concentration- 194.6 ng/dl (N-80-160) A suggested treatment for Helen is to remove her thyroid gland and give her doses of synthetic T4.The following blood serum results show the changes in her thyroid hormone levels across 3 months TSH Timepoint Pre-operation Directly after the operation One month post-operation Two months post-operation Three months post-operation T4 15.2 0.2 1.2 13.1 0.4 10.4 1.1 10.3 2.8 1 12. Using the data provided; three months post-operation Helen's T3 levels will be this is due to T4 and being converted to T3 at the target tissue?Explanation / Answer
(I) T3 level will be also decreases but in thyroid removal patient it varies between 4:1 to 2:1 ratio.
(II) T4 hormone is converted by an enzyme named 5'-deiodinase to the active T3 hormone in target tissues.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.