Endocrine System Helen is a 45-year-old housewife, lately she\'s noticed that sh

Question

Endocrine System Helen is a 45-year-old housewife, lately she's noticed that she has been losing weight but maintaining her caloric intake and still going for her 2 powerwalks a week, although she feels like she needs to start running as when she gets home she is full of beans. She has also been increasingly irritated with her husband Timothy who has been putting the electric blanket on in bed when she is already overheating Helen goes to her local clinic to see Dr, Dresden, who notes that her body temperature is above average and she has in fact lost 10 kg since her regular check-up 4 months ago. Dr. Dresden orders a blood test to check Helen's thyroid hormone levels T4 concentration 15.2 ug/dl (N-45-12.5), T3 concentration= 1945 ng/dl (N=80-160) A suggested treatment for Helen is to remove her thyroid gland and give her doses of synthetic T4.The following blood serum results show the changes in her thyroid hormone levels across 3 months T4 15.2 0.2 1.2 13.1 0.4 10.4 1.1 10.3 1 TSH Timepoint Pre-operation Directly after the operation One month post-operation Two months post-operation Three months post-operation 2.8 12. Using the data provided; directly post-operation TRH will be This is due to

Explanation / Answer

Using the data provided; directly post-operation TRH will ne 2.8 ,this is due to thyroidectomy as thyroid is removed but pituitary gland is still present which secretes TSH.Synthetic thyroids are thus provided in aid of TSH.If TSH is high,high dose synthetic T4 will be given,if TSH is low,low dose synthetic T4 will be given.

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