Insulin is a water-soluble hormone. Therefore it a.is secreted by exocytosis and
ID: 3521282 • Letter: I
Question
Insulin is a water-soluble hormone. Therefore it
a.is secreted by exocytosis and travels unbound in the blood stream.
is secreted by simple diffusion and travels bound to proteins in the blood stream.
is secreted by exocytosis and travels bound to proteins in the blood stream.
is secreted by simple diffusion and travels unbound in the blood stream.
a.is secreted by exocytosis and travels unbound in the blood stream.
b.is secreted by simple diffusion and travels bound to proteins in the blood stream.
c.is secreted by exocytosis and travels bound to proteins in the blood stream.
d.is secreted by simple diffusion and travels unbound in the blood stream.
Explanation / Answer
Answer - C - Insuline is secreted by exocytosis and travels bound to proteins in the blood stream.
Insulin is stored in large dense core vesicles. It is released by the mechanism of exocytosis. It is a multistage process that involves transport of vesicles to the plasma membrane, their docking, priming and finally their fusion with the plasma membrane. Some protein components are required for this process are identified in beta cells. Glucose depolarizes the beta-cell membrane and the ensuing Ca2+ influx through voltage-dependent channels forms a main stimulus for insulin exocytosis.
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