Insulin is an important hormone that regulates glucose levels in the blood. The

Question

Insulin is an important hormone that regulates glucose levels in the blood. The insulin protein is encoded by the INS gene, which is expressed primarily by the ?-islet cells of the pancreas. These cells produce the insulin protein and secrete it into the bloodstream. Other cells in the pancreas do not produce insulin. If you examined the chromatin in the regulatory region of the INS gene in different cell types, you would expect to observe ____________ in the ?-islet cells and ____________ in the other pancreatic cells.

DNA methylation; histone H3K9 methylation

histone H3K9 methylation; histone H3K4 methylation histone

H3K4 methylation; DNA methylation

Explanation / Answer

If you examined the chromatin in the regulatory region of the INS gene in different cell types, you would expect to observe DNA methylation in the ?-islet cells and histone H3K9 methylation in the other pancreatic cells.

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