4) As you know, tRNA molecules are highly modified during their maturation. The

Question

4) As you know, tRNA molecules are highly modified during their maturation. The most striking of these modifications are the chemical alterations of the bases. Uracil (U) is modified to thymine (T) or dihydrouracil (D), or it is moved on the nucleotide to form pseudouridine (psi). Guanine (G) is modified to give inosine (I) or methylguanine (Gm). Cytosine (C) is methylated to give methylcytosine (Cm). Below is a hypothetical sequence of part of a tRNA. What is the sequence of the double-stranded DNA from which this RNA was transcribed? Don't forget to indicate the appropriate polarities. (4 pts) 5'-GCGCmATGUIpsiAAUCmDG-3'

Explanation / Answer

5'- CAG ATT ACA CAT GCG C -3'

3'- GTC TAA TGT GTA CGC G -5'

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