24 mtgh - 1.2mm Hg Pco chart, how will the patient\'s body compensate for his pH

Question

24 mtgh - 1.2mm Hg Pco chart, how will the patient's body compensate for his pH disturbance? th an acute exacerbation of asthma and treatment is begun with Beta-2- er and his respiratory improvement is monitored with a spirometer. Chris is instructed o asked to take the deepest breath possible and blow into the device as much air as he agonists (Albuterol) which cause bronchodilatation, and steroids to reduce airway inflammation. Chris y into the device for One second. This will measure his Forced Expiratory Volume (FEV). can. This measures Forced Vital Capacity (FVC) Chris is als LITERS 2 Systematic use of spirometry is critical in assessing the severity of asthma, the patient esponses to therapy, and the disorder's course over a lifetime. During an asthma att EVi and FVC are reduced in asthma because of obstruction to airflow, 7. Measuring improvement with a spirometer, what changes in forced expiration volume can w expect to see? Journal for Respiratory Care Practitioners 1999;12:57-61,75.

Explanation / Answer

Q6 patients body compensate the body pH change in a very specific way as explained below-

In metabolic Acidosis conditions - their is decrease in the level of Hco3- ions in body, whih can be compensated by using respiratory hyperventilation it elliminates Co2, from extracellular fluid, and by mass reduces the H ion concentration. And also by renal compensation by increased excretion of fixed H ions with increase in Nh4 , in type A intercalated cells, increased h ions secretion.

Respiratory acidosis - mainly corrected by renal compensation by increased H ions excretion & increased absorption of new Hco3- formed.

Metabolic alkalosis- is due to addition of Hco3- or loss of H ions. Compensate by - respiratory hypoventilation, will elevate pco2 and normalise PH also by renal decrease H ion secretion.

Respiratory alkalosis- due to decrease pco2 level is compensate by- renal mainly by excreted out H ions as titrable acid and Nh4+.

In asthma patients- due to initial sudden attack & respiratory compromise their is hyperventilation lead to initially respiratory alkalosis. Which is followed by complete arrest of respiration lead to accumulation of Co2 later, lead to respiratory acidosis.

Q7 in asthma patient as the FEV1/ FVC ratio is lower than 0.7 which is normally higher than 0.7 in normal person.

Asthma is obstructive lung disease in which their is FEV1 drops much higher than FVC show decrease in ratio.

But after giving treatment patient conditions improved and the FEV1 value will be increased and when the FEV1/FVC ratio improved by more thsn 12% after bronchodialators than diagonosis of asthma is confirmed.

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