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Format Font Tools Table Window Help roductive System Questions.docx Word File Edit View Search in Document Home Layout Document Elements Tables Charts SmartArt Review Styles Aa (Body) Text Box Themes 4 Explain the sequence of events by which the male accessory sex organs and external genitalia are produced. What occurs when a male embryo lacks receptor proteins for testosterone? What occurs when a male embryo lacks the enzyme Sa-reductase? 13, Print Layout View Sec 1 Pages:2 o1 2 100% 20,068 MacBook Pro

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Development of male sex organs and accessory organs: the gonads begin to attain sexual characteristics from the 7 th week,development of gonads is the 1st stage in male sex organ development it includes a) development and migeation of primitive germ cells , 2)sertoli cells, 3)leydig cells and with the formation and canalization of the seminiferous tubules, 5th week proliferation of the cells of the coloemic epithelium and mesoderm to form 2 gondal ridges along the dorsal body wall medial to the mesenephrons , 6th week migration of the primitive germ cells fom the yolk sac to the gondal ridges by amoeboid movement to form spermatogonis later on,7th week formation of sertoli cells from the coloemic epithelium part of the gonadal ridges, 8th week formation of ledyig cell from the mesodermal cells part of the gonadal ridge, development of internal genital ducts: a)predifferentiation stage : until 8th week , gondal ridge, mesenephric duct, paramesonephric duct and urogentialsinus, b) post differentiation stage: 1)regression of pmd, sertoli cells secrete MIS, regression of PMD except for 2 rudimentary portions , appendix testis, prostatic utricles2) progression of MD, the XY genes differentiation testicular and formation of leydif and sertoli cells, the leydig cells release the testosterone reults in MD cells proliferation which results in epididymis ,vas and ejaculatory duct. development of external genitalia : by the action of tertosterone genital tubercle elongates to form the penis, and urogenital folds devlops into penile urethra and urethralmeatus.development of accessory glands :a) seminal vesicles : it secrete alkaline fluid that contain fructose as energy source enzymen prostaglandins b) prostate glands : secrete citrate and enzymes to break downthe semen clot once inside female reproductive tract. - deficiency of 5alpha reductase is an auotsomal recessive diorder that imapirs the conversion of testosterone to dihydrotestosterone , in affected males the internal urogential tract virilizes normally but formation of the male external genitalia is variably impaired and is usually female in character in affected males raised as women this disorder is commonly assoicated witha change to male gender role behavior after the time of expected puberty. -lack of receptor protein for testosterone is an xlinked genetic condition, generally its lack effect the fertility but no effect on tissues, both internal and external genitalia.

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