4 The disease diabetes mellitus is due sensitivity of target cells to circulatin

Question

4 The disease diabetes mellitus is due sensitivity of target cells to circulating insulin. How would this affect the leve destruction of o either destruction of the cels that produce insulin or a decrease in l of glucose in the blood? Why? A type of tumor in the pancreas called a glucagonoma produces and releases excess glucagon into the blood How would this affect the level of glucose in the blood? Would the overall effect on blood glucose differ from that of type I diabetes mellitus? Why or why not? 5 In the condition hyperthyroidism, patients have elevated levels of both T3 and T4 due to a malfunction of the immune system that causes the thyroid gland to overproduce thyroid hormones. Do you think the negative feedback loops would lead to high levels of TSH or low levels of TSH? Explain. 6 7 In case 3 of Exercise 16-4 (p. 437), we saw that Professor Purple had insufficient antidiuretic hormone (ADH) However, the opposite condition can also occur in which excess ADH is present, called syndrome of inappropriate

Explanation / Answer

how diabetes mellitus affects the level of glucose /

see diabetes mellitus is the disease where there is a reduction of insulin production of our body. the work of the insulin hormone is to convert the glucose into energy. so if the glucose level stays high it will damage our body by hardening of the blood vessels and the pancreas is permanently damaged.

why?

normally when the blood glucose levels are controlled by insulin. the insulin lowers the blood glucose level. when blood glucose level increases insulin is released by the pancreas to lower it.in case of Diabetes Mellitus, the patient is unable to release the insulin which causes hyperglycemia.

how would glucagonoma affect the blood glucose level

Glucagonoma is a rare tumor in the pancreas. Glucagon is a hormone produced by the pancreas that works with insulin to control the sugar level in blood. Glucagonoma tumor cells produce large amounts of glucagon, and these high levels create painful symptoms.so when large quantities of glucagon are produced the sugar is not stored by the cell instead the sugar is stored in the blood.

glucagonoma acts quite similar to diabetes. the blood sugar level increases a lot. causing,

excessive thirst and hunger due to high blood sugar

frequently waking up at night to urinate

diarrhea

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